They open narrowed blood vessels, which helps blood flow through your lungs more easily. These can include: Sildenafil (Revatio) and tadalafil (Adcirca) Your doctor may prescribe other drugs to treat your PAH. Tell your doctor about all medications you’re taking. Riociguat also interacts with antacids and cigarette smoke. These include sildenafil and tadalafil, which are two other drugs used to treat PAH. bleeding, including bleeding in your breathing passages.Serious side effects of this drug can include: Because of these risks, you can only get this drug through certain certified pharmacies.Ĭommon side effects of Riocoguat can include: Riociguat (Adempas), an oral tablet, is one example of this type of drug. yellowing of your skin or the whites of your eyes.This means your blood can’t carry oxygen as well as it should. Serious side effects of these drugs can include: They include:Ĭommon side effects of endothelin receptor antagonists can include: This can make it even more difficult for blood and oxygen to flow to the rest of your body.Īll of the drugs in this group are oral drugs. If you have too much of it, it can slowly build up on the walls of your blood vessels.Īs it builds up, your blood vessels become narrower. Endothelin is a natural substance in your blood. Endothelin receptor antagonistsĮndothelin receptor antagonists work by reversing the effect of endothelin. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. Your doctor may also make changes to your diet and your medications to prevent dangerous interactions. They’ll likely do routine blood tests to check how the drug affects your body. If you take a blood thinner, your doctor will monitor your condition closely. Warfarin (Coumadin) is one example of an anticoagulant.Ī common side effect of this class of drugs is increased bleeding if you’re injured or cut. They also stop clots from blocking the small pulmonary arteries. Anticoagulants are blood-thinning drugs that prevent blood clots from forming. People with PAH have a higher risk of blood clots in their lungs. This medication may be better at slowing the progression of PAH than improving the symptoms of PAH. Selexipag (Uptravi) is another vasodilator for PAH. Eventually, you only take the oral form of this drug. Your doctor slowly increases your oral dosage and decreases your injection dosage. Then you start taking part of your dosage in the tablet form. “Extended release” means the drug is released slowly into your body.įirst, you receive treprostinil sodium as an injection from your doctor. Treprostinil sodium is also available as an extended-release oral tablet that’s marketed under the brand name Orenitram. Your doctor gives you this drug through an IV, or you may also receive it subcutaneously, or under your skin. Treprostinil sodium (Remodulin)Īnother vasodilator is called treprostinil sodium (Remodulin). Your doctor attaches the pump to you, but you give the drug to yourself as you need it. These vasodilators use a pump that’s often on a belt you wear around your waist. These drugs include epoprostenol (Flolan, Veletri). Other vasodilators are given through an intravenous (IV) injection, which means the drug is injected into your vein. These drugs are inhaled through a nebulizer, which is a breathing device that delivers medication to your lungs. These include iloprost (Ventavis) and treprostinil (Tyvaso). They can help more blood and oxygen flow through your body.Ĭommon side effects of these drugs can include:Įxamples of vasodilators include: Iloprost (Ventavis) and treprostinil (Tyvaso) These drugs work to open blocked and narrowed blood vessels in your lungs. Many people with PAH need to take vasodilators, or blood vessel dilators. There are several types of medications used to treat PAH. To properly manage your condition, you need to take your PAH medication long term. Together, you’ll make a treatment plan, which includes taking medications. Once you’re diagnosed with PAH, you’ll work closely with your doctor.
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